How to Choose the Best MS Treatment for Your Lifestyle?

It is common for people with MS to feel overwhelmed by all of the treatments available. To make things simpler, it may be helpful to understand the types of treatment that are most commonly used. These can be broken into three categories: medications, lifestyle measures, and procedures. Below is an overview of what these mean and links to more information on each type of treatment.

Medications for multiple sclerosis fall into four general groups. Some are specifically approved for treating relapses (also known as flares). Others are approved for preventing future flares or reducing their severity if they occur. Still, others are only available by special permission from the U.S. Food and Drug Administration (FDA) because they have not been extensively studied in controlled clinical trials among people with MS.

People with relapsing-remitting MS (RRMS) may be prescribed several of these medications:

This category consists of three FDA approved therapies that reduce the number and severity of exacerbations in RRMS:

Some people with primary progressive multiple sclerosis (PPMS) or secondary progressive multiple sclerosis (SPMS) can achieve stabilization using one of these disease-modifying treatments:

For people who do not respond to other therapies, mitoxantrone is available with special permission from the FDA as a last-resort treatment. Although it has been extensively studied in clinical trials among people with MS, its side effects are serious enough that it should only be used after careful consideration of the benefits versus the risks.

Lifestyle Interventions:

The following are some of the effective lifestyle interventions that can help manage MS over time. These may be used alone or in conjunction with drug therapy, depending on individual needs and preferences:

Procedures:

Some procedures may help manage specific symptoms resulting from MS. Options include:

In addition to any procedure related to specific MS symptoms, several surgical options exist for unrelated problems and other health conditions common among people with MS. The risks and benefits should always be carefully considered before choosing surgery.

Numerous studies have shown that physical activity helps reduce the risk of developing disability in people with RRMS. Movement can help control spasticity (stiffness or tightness) by increasing blood flow to muscles and stretching them after periods of inactivity.

Aerobic exercise, such as walking, bicycling, swimming, or stationary bicycling, is best for maintaining cardiovascular fitness. The benefits of participation in a regular physical activity program extend beyond just improved cardiovascular conditioning—it also helps strengthen muscles and bones and improves self-esteem.

The study noted that people with MS have an average life expectancy 10 years lower than the general population. However, the gap may be narrowing slightly due to increasing access to health care and advancements in treatment.

Newer studies have found a “small but significant” decrease in mortality among those treated within one year of diagnosis compared to those who waited longer for treatment. Improved treatments are expected to continue increasing lifespan. Some researchers have also found that MS is less aggressive in warmer climates, suggesting that “living at higher latitudes (and hence receiving less sunlight) may increase the risk of MS.”

However, it may be important for people living with multiple sclerosis to maintain a healthy weight. A study conducted in 2010 showed that individuals who were overweight or obese faced more health problems than those with an average body mass index (BMI). Some of these problems included lower mental health quality of life and greater fatigue. Thus, maintaining a healthy weight can benefit overall wellbeing for someone diagnosed with MS.

 Best ms treatment in the world:

If you’re interested in the best treatment like Chronic Myelogenous Leukemia (CML) and Acute Promyelocytic Leukemia (APL), this article will be of interest to you. Over the next few paragraphs, we discuss some of the recent developments in treatments for these diseases and what Dr. Joseph Mikhael suggests as a treatment plan for patients diagnosed with them.

Good news for ms patients:

First, let’s start with an overview of the standard treatment for CML. For many years now Imatinib (trade name Gleevec) has been used as a first-line treatment for CML. This is the drug that was developed by Novartis Pharmaceuticals which showed spectacular results in clinical trials and became one of the most famous cancer drugs ever developed.

Imatinib works by blocking the protein tyrosine kinase enzyme, called BCR-ABL, which plays an important role in cell division and proliferation. The inhibition of this protein stops the formation of new blood cells in CML patients who over-express it, slowing down tumor growth significantly.

Good news for ms patients:

This is because there are some concerns about the long-term safety profile of imatinib and other tyrosine kinase inhibitors (TKO). For example, there have been reports from CML patients treated with this that skin cancers tend to appear 10 years or more after starting therapy. In addition, since these drugs target enzymes involved in cell division and proliferation, they increase the risk of developing leukemia later on.

Drugs to avoid in multiple sclerosis:

Now let’s take a look at the treatment options for APL. Cases of this rare type of leukemia are often very challenging both to diagnose and treat. The disease can be caused by many different genetic variations which is why it’s so hard to determine an effective treatment plan.

One current approach is to use arsenic trioxide (ATO) as the initial course of treatment, with all-trans retinoic acid (RA), chemotherapy, dexamethasone, and etoposide added in after six months if needed.

Drugs to avoid in multiple sclerosis:

This combination has been used successfully but there are some concerns that ATO might cause kidney toxicity, although this doesn’t typically happen unless you’re diagnosed with chronic kidney disease or some other type of kidney problem.

Best ms treatment in the world:

Without a doubt, drug toxicity is an ongoing concern for any doctor treating cancer patients. Sometimes you can prevent some of these toxicities by using certain types of medication before others (for example, not prescribing TKis to patients who already have skin cancer).

But even if this strategy works it doesn’t always mean that your patient will be completely safe from harmful side effects; they’ll still need to undergo regular monitoring and check-ups at their oncology clinic to make sure things are okay.

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